Monte Carlo Simulation Study on the Optimal Neutron Energy and Boron Concentration for SARS-COV-2 Inactivation through BNCT

Researchers have been exploring various radiation therapies to treat COVID-19 patients ranging from mild severe. One technique that has shown promise is Boron Neutron Capture Therapy (BNCT). This therapy involves administering of 10B isotope the targeted area, which then exposed chargeless neutrons. These neutrons can be absorbed by areas with high concentrations 10B. When react (10B + n?7Li 4He reaction), it results in transfer highly ionizing energy, causing confined lethality and destroying area. In this study, we used Particle Heavy Ion Transport Code System simulation evaluate whether could effective as an anti-viral therapy. The study creating a model SAR-COV-2 target phantom's geometry defining its chemical composition collect data. It was found out when tested at different neutron energies (30 ppm, 50 100 ppm), sufficient amount dose cause biological damage Sars-CoV-2 enveloped protein achieved 30 ppm boron concentration energy 1.0x10-10 MeV.